Cyclic(alkyl)(amino)carbene ruthenium complexes for <i>Z</i>-stereoselective (asymmetric) olefin metathesis
نویسندگان
چکیده
The first Z -stereoselective catechodithiolate ruthenium complexes containing achiral and chiral cyclic(alkyl)(amino)carbene ligands are reported.
منابع مشابه
Enantioselective Olefin Metathesis with Cyclometalated Ruthenium Complexes
The success of enantioselective olefin metathesis relies on the design of enantioenriched alkylidene complexes capable of transferring stereochemical information from the catalyst structure to the reactants. Cyclometalation of the NHC ligand has proven to be a successful strategy to incorporate stereogenic atoms into the catalyst structure. Enantioenriched complexes incorporating this design el...
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Olefin metathesis is a prevailing method for the construction of organic molecules. Recent advancements in olefin metathesis have focused on stereoselective transformations. Ruthenium olefin metathesis catalysts have had a particularly pronounced impact in the area of stereoselective olefin metathesis. The development of three categories of Z-selective olefin metathesis catalysts has made Z-ole...
متن کاملKey processes in ruthenium-catalysed olefin metathesis.
While the fundamental series of [2+2]cycloadditions and retro[2+2]cycloadditions that make up the pathways of ruthenium-catalysed metathesis reactions is well-established, the exploration of mechanistic aspects of alkene metathesis continues. In this Feature Article, modern mechanistic studies of the alkene metathesis reaction, catalysed by well-defined ruthenium complexes, are discussed. Broad...
متن کاملHighly active chiral ruthenium catalysts for asymmetric ring-closing olefin metathesis.
The synthesis of olefin metathesis catalysts containing chiral, monodentate N-heterocyclic carbenes and their application to asymmetric ring-closing metathesis (ARCM) are reported. These catalysts retain the high levels of reactivity found in the related achiral variants (1a and 1b). Using the parent chiral catalysts 2a and 2b and derivatives that contain steric bulk in the meta positions of th...
متن کاملAmino acids as chiral anionic ligands for ruthenium based asymmetric olefin metathesis.
Several amino acid ligands were introduced into the Hoveyda-Grubbs 2nd generation complex by a facile anionic ligand exchange. The chiral pre-catalysts obtained displayed enantioselectivity in asymmetric ring-closing and ring-opening cross-metathesis reactions. Reduction of the lability of the carboxylate ligands was found to be cardinal for improving the observed enantiomeric product enrichment.
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ژورنال
عنوان ژورنال: Catalysis Science & Technology
سال: 2023
ISSN: ['2044-4761', '2044-4753']
DOI: https://doi.org/10.1039/d2cy01795d